Hyperinfection syndrome or disseminated strongyloidiasis (DC 6325)

Body system: Infectious Diseases, Immune Disorders, and Nutritional DeficienciesRegulation: 38 CFR § 4.88b

Hyperinfection syndrome and disseminated strongyloidiasis are severe forms of Strongyloides stercoralis infection where the parasites multiply rapidly and spread beyond the gut (intestines, lungs, central nervous system, skin), often in immunocompromised hosts. Can be life-threatening if untreated. The VA rates this condition at 100% during active disease, and per the Note in 38 CFR § 4.88b, the 100% rating CONTINUES past the end of treatment. Six months after treatment ends, the VA conducts a MANDATORY examination to determine the new rating, any reduction is subject to the due-process rules of 38 CFR § 3.105(e). After that exam, any lasting damage is rated separately under the appropriate body-system codes (gastrointestinal damage under the digestive system codes, pulmonary scarring or chronic respiratory impairment under the respiratory codes, neurological residuals (e.g., meningitis sequelae) under § 4.124a, septic complications, and any other body-system damage) and combined under § 4.25.

Rating levels

  • 100% — You qualify for 100% during active hyperinfection syndrome or disseminated strongyloidiasis. Per the Note below, the 100% rating CONTINUES past the cessation of treatment for active disease, with a mandatory VA examination six months after treatment ends to determine the appropriate rating going forward.
  • -1% — Two timing rules apply after active treatment ends. RULE 1: the 100% rating CONTINUES past the cessation of treatment, it does not drop the day treatment ends. RULE 2: six months after treatment ends, the VA must perform a MANDATORY examination to determine the new rating going forward. Any rating reduction from that exam (or any later exam) is subject to the due-process protections of 38 CFR § 3.105(e). After that point, any lasting damage from hyperinfection syndrome or disseminated strongyloidiasis is rated SEPARATELY under whichever body-system code best captures the deficit, including gastrointestinal damage under the digestive system codes, pulmonary scarring or chronic respiratory impairment under the respiratory codes, neurological residuals (e.g., meningitis sequelae) under § 4.124a, septic complications, and any other body-system damage, then combined under § 4.25.

Disclaimer: This tool is for informational purposes only and is not legal or medical advice. Always consult with your VSO representative or a qualified veterans benefits attorney for guidance on your specific claim.