Chorea, Huntington's (DC 8106)
Huntington's chorea (Huntington's disease) is a hereditary, progressive neurodegenerative disorder caused by an autosomal-dominant CAG-repeat expansion in the HTT gene. It produces involuntary choreiform movements, progressive cognitive decline, and psychiatric symptoms (depression, irritability, psychosis), typically with adult-life onset and inexorable progression to dementia and total disability over 10-20 years. The VA rates DC 8106 as Sydenham's chorea: 100% (pronounced, progressive grave), 80% (severe), 50% (moderately severe), 30% (moderate), 10% (mild). Although Huntington's is a familial disease, late-adult-life onset means it is considered a ratable disability when it manifests during or after service.
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